Description

Cowan et al identified changes in the brain MRI scans of neonates that are indicative of antenatal or perinatal insults. These findings can aid in the evaluation of an infant with neonatal encephalopathy. The authors are from Hammersmith Hospital, University Medical Centre at Utrecht and Catholic University Rome.


 

MRI features suggesting a developmental or antenatal insult:

(1) irregular ventricular dilatation

(2) enlarged extracerebral space

(3) widening of the interhemispheric fissure

(4) focal infarction with atrophy

(5) organized hemorrhage

(6) marked asymmetry in cerebral structures

(7) cortical dysplasia, structural anomalies, etc indicative of a developmental anomaly

(8) cystic degeneration

 

MRI features suggesting a perinatal insult:

(1) acute edema with brain swelling

(2) highlighting of the cortex

(3) acute or subacute hemorrhage (extracerebrl, parenchymal, intraventricular)

(4) evolving infarction in an arterial distribution

(5) evolving infarction in a parasagittal or watershed distribution

(6) loss of differentiation between grey and white matter, focal or global

(7) abnormal signal intensity in the thalami and basal ganglia

(8) abnormal signal intensity in the posterior limb of the internal capsule (PLIC)

 


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