MRI Findings of Tateishi et al Associated with the Grade of a Myxoid-Round Cell Liposarcoma

Description

Tateishi et al evaluated MRI images from patients with myxoid-round cell liposarcomas. They identified findings associated with intermediate and high grade tumors, which tend to have a worse prognosis. The authors are from National Cancer Center Hospital and Research Institute, Tsukiji, Chuo-Ku, Tokyo.

Parameters:

(1) diameter in centimeters

(2) lobulations

(3) thick septae

(4) enhancement with contrast

(5) globular and nodular enhancement

Parameter	Finding	Points
diameter in cm	<= 10 cm	0
	> 10 cm	1
lobulations	present	0
	absent	1
thick septae	absent	0
	present	1
enhancement	absent or not pronounced	0
	pronounced	1
globular and nodular enhancement	absent	0
	present	1

number of factors with intermediate to high grade liposarcoma =

= SUM(points for the 5 parameters)

Additional factors favoring an intermediate or high grade tumor:

(1) deep location (not superficial)

(2) irregular contours

(3) absence of thin septae

(4) absence of a tumor capsule

(5) high intensity signal pattern

The presence of pronounced enhancement was the most significant factor for predicting poor survival on multivariate analysis. The presence of pronounced enhancement was associated with a 10 year survival of 42% vs 100% if it was absent.

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Description

Specialty

ICD-10