Description

Bedos et al identified risk factors for death within 3 months for HIV-infected patients with neurologic failure admitted to the intensive care unit (ICU). The authors are from Bichat-Claude Bernard University Hospital and Saint-Louis Hospital in Paris.


 

Outcome: death within 3 months of admission to the ICU

 

Parameters:

(1) Glasgow Coma Score (GCS)

(2) brain stem involvement

Parameter

Finding

Points

Glasgow Coma Score

7 to 15

0

 

3 to 6

1

brain stem involvement

no

0

 

yes

1

 

total number of risk factors =

= SUM(points for the 2 parameters)

 

Interpretation:

• minimum number of risk factors: 0

• maximum number of risk factors: 2

• The risk of death is associated with the number of risk factors present. These reflect severe neurological involvement.

 

Limitations:

• The study was performed before HAART was available.

• Many of the patients were admitted with opportunistic infections (especially cerebral toxoplasmosis). Most of the patients were AIDS Stage IV (CDC).

 


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