Description

Lee et al reported the Morphic Malnutrition Score (MMS) to screen adults for severe malnutrition. The authors are from the University of Michigan, University of Wisconsin and VA Ann Arbor Healthcare System.


Patient selection: adult

 

Analysis: CT scan of thorax and abdomen

 

CT cross-sections (see Figure 2):

(1) at T12: area of the left and right dorsal muscles

(2) at L4: area of both psoas muscles

(3) at L3: area of subcutaneous fat all around the torso

 

Parameters:

(1) T12 dorsal muscle group area in square mm, expressed as percentile of the population

(2) L4 total psoas muscle area in square mm, expressed as percentile of the population

(3) L3 subcutaneous fat area in square mm expressed as percentile of the population

 

morphic malnutrition score =

= 10.55 - (0.0343 * (percentile for subcutaneous fat area)) - (0.0274 * (percentile for total psoas area)) - (0.0494 * (percentile for dorsal muscle area)

 

Interpretation:

Normal patients had an MMS with mean 3.8 +/- 2.0.

The optimal cutoff for severe malnutrition was > 6.1.

 

Performance:

The area under the ROC curve was 0.89 in the training set and 0.94 in the validation set.


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