At the 2005 Montreal World Congress of Gatroenterology a classification for ulcerative colitis (UC) was proposed to describe the extent and severity of disease involvement. This can improve communication about a patient affected by the disease.
Parameters:
(1) extent (E)
(2) severity (S)
Extent
Term
Code
limited to the rectum (distal to rectosigmoid junction)
ulcerative proctitis
E1
limited to colon distal to the splenic flexure
distal (left-sided) UC
E2
involvement of colon proximal to the splenic flexure as well as distal
extensive UC (pancolitis)
E3
Severity
Term
Code
clinically asymptomatic
clinical remission
S0
>= 4 stools per day with or without blood; no systemic illness; normal ESR and other inflammatory markers
mild disease
S1
>= 5 stools per day with or without blood; minimal signs of systemic illness
moderate disease
S2
>= 6 stools with blood per day; signs of systemic illness
severe disease
S3
Signs of systemic illness for S3 include:
(1) pulse >= 90 beats per minute
(2) temperature >= 37.5°C
(3) anemia (hemoglobin < 10.5 g/dL)
(4) ESR >= 30 mm in first hour
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