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Monitoring Response to Therapy for Paget's Disease Using Urine Markers of Bone Resorption

Specialty:

Orthopedic Surgery, Sports Medicine & Rehabilitation

Objective:

ICD-10:

Description:

Excretion of several compounds in the urine can be used as a measure of osteoclastic activity, which is increased in Paget's disease of bone. Effective therapy with bisphosphonates or other drugs causes a reduction of these chemicals in the urine.

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