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Monitoring Response to Therapy for Paget's Disease Using Serum Alkaline Phosphatase

Specialty:

Orthopedic Surgery, Sports Medicine & Rehabilitation

Objective:

ICD-10:

Description:

Serum alkaline phosphatase is a measure of osteoblastic activity, which is increased in Paget's disease of bone. Effective therapy with bisphosphonates or other drugs causes a reduction in alkaline phosphatase activity.

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