A patient receiving an oral anticoagulant should be monitored for warfarin-related nephropathy (anticoagulation-related nephropathy) during therapy.
Testing periods are separated into the initiation phase (first 3 months) and maintenance phase (thereafter).
Since chronic kidney disease is a risk factor for anticoagulation-related nephropathy, testing is also affected by the patient's GFR in mL per minute.
Additional instructions:
(1) Rapid changes in the INR should be avoided.
(2) The patient should report any hematuria.
Testing protocol:
(1) serum creatinine in mg/dL
(2) INR
Testing during the initiation period (first 3 months) every 3-4 weeks.
Testing during the maintenance phase is determined by the anticoagulant and GFR.
GFR
Warfarin
Direct Oral
> 60
6 months
12 months
30 to 60
2-3 months
< 60
3 months
To read more or access our algorithms and calculators, please log in or register.
Specialty: Nephrology, Clinical Laboratory, Pharmacology, clinical
