C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR) can be used to monitor a patient with Crohn’s disease.
A relapse in Crohn’s Disease was defined by:
(1) a CDAI > 150 AND
(2) increase in the CDAI from baseline > 100
(1) CRP in mg/L
(2) ESR in mm in the first
CRP in mg/L
<= 20 mg/L
> 20 mg/L
ESR in mm during the first hour
<= 15 mm
> 15 mm
total score =
= SUM(points for both parameters)
• minimum score: 0
• maximum score: 2
• A patient with a score of 0 was unlikely to have a relapse within the next 8 weeks.
• A patient with a score of 2 was 8 times more likely to have a relapse within the next 8 weeks.
• A markedly elevated CRP is associated with abscess or other bacterial complication.
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