Monitoring CRP and ESR in a Patient with Crohn’s Disease

 

A relapse in Crohn’s Disease was defined by:

(1) a CDAI > 150 AND

(2) increase in the CDAI from baseline > 100

 

Parameters:

(1) CRP in mg/L

(2) ESR in mm in the first hour

Parameter	Finding	Points
CRP in mg/L	<= 20 mg/L	0
	> 20 mg/L	1
ESR in mm during the first hour	<= 15 mm	0
	> 15 mm	1

 

total score =

= SUM(points for both parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 2

• A patient with a score of 0 was unlikely to have a relapse within the next 8 weeks.

• A patient with a score of 2 was 8 times more likely to have a relapse within the next 8 weeks.

• A markedly elevated CRP is associated with abscess or other bacterial complication.