Moebius Syndrome may represent several disorders that share certain neurologic findings.


“Classic” criteria:

(1) congenital facial nerve palsy, which may be unilateral or bilateral

(2) abduction deficit of the eyes (abducens palsy)

MacKinnon et al added normal/full vertical motility as a third criterion.


Other findings may include:

(1) orofacial malformations

(2) limb defects

(3) musculoskeletal abnormalities

(4) cognitive and behavioral abnormalities

(5) other cranial nerve palsies


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