McBride et al reported a modified SOFA (Sequential Organ Failure Assessment) score for use in patients with dengue fever. The authors are from Oxford University, Brighton and Sussex Medical School, University of Medicine and Pharmacy of Ho Chi Minh City and Imperial College London.
Patient selection: severe dengue fever, in the ICU
Measure |
Finding |
Points |
PaO2 to FIO2 ratio |
>= 400 mm Hg |
0 |
|
315 – 399.99 mm Hg |
1 |
|
235 to 314.99 mm Hg |
2 |
|
150 – 234.99 mm Hg |
3 |
|
>= 150 mm Hg and respiratory support |
3 |
|
< 150 mm Hg and respiratory support |
4 |
platelet count |
>= 150,000 per µL |
0 |
|
100,000 to 149,999 per µL |
1 |
|
50,000 to 99,999 per µL |
2 |
|
20,000 to 49,999 per µL |
3 |
|
< 20,000 per µL |
4 |
serum bilirubin |
< 1.2 mg/dL |
0 |
|
1.2 – 1.9 mg/dL |
1 |
|
2.0 – 5.9 mg/dL |
2 |
|
6.0 – 11.9 mg/dL |
3 |
|
>= 12.0 mg/dL |
4 |
hypotension |
mean arterial pressure >= 70 mm Hg and pulse pressure >= 20 mm Hg |
0 |
|
mean arterial pressure < 70 mm Hg or pulse pressure 10-19 mm Hg, no pressor agents used |
1 |
|
pulse pressure < 10 mm Hg |
2 |
|
dobutamine, any dose |
2 |
|
dopamine <= 5 µg per kg per min |
2 |
|
dopamine > 5 to 15 µg per kg per min |
3 |
|
dopamine > 15 µg per kg per min |
4 |
|
epinephrine <= 0.1 µg per kg per min |
3 |
|
epinephrine > 0.1 µg per kg per min |
4 |
|
norepinephrine <= 0.1 µg per kg per min |
3 |
|
norepinephrine > 0.1 µg per kg per min |
4 |
Glasgow coma score |
15 |
0 |
|
13 - 14 |
1 |
|
10 - 12 |
2 |
|
6 - 9 |
3 |
|
3 - 5 |
4 |
serum creatinine or urine output |
serum creatinine < 1.2 mg/dL |
0 |
|
serum creatinine 1.2 – 1.9 mg/dL |
1 |
|
serum creatinine 2.0 – 3.4 mg/dL |
2 |
|
serum creatinine 3.5 – 4.9 mg/dL |
3 |
|
urine output 200 - 499 mL per day |
3 |
|
serum creatinine >= 5.0 mg/dL |
4 |
|
urine output < 200 mL per day |
4 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 24
• The higher the score the more severe the dengue fever.
Specialty: Infectious Diseases