Akin et al used a modified SOFA-RV score for evaluating a patient with cardiogenic shock on veno-arterial ECMO or other mechanical circulatory support. The authors are from Erasmus MC, Haga Teaching Hospital, Columbia University, Langone Medical Center and Pontificia Universidad Catolica de Chile.
Patient selection: cardiogenic shock on veno-arterial ECMO or other mechanical circulatory support
Parameters (SOFA score plus right ventricular score):
(1) PaO2 to FIO2 ratio and/or mechanical ventilation
(2) platelet count per microliter
(3) Glasgow coma scale (GCS)
(4) serum total bilirubin in mg/dL
(5) mean arterial pressure (MAP) in mm Hg or vasopressor therapy (in µg per kg per min)
(6) serum creatinine in mg/dL
(7) right ventricular score
Parameter |
Finding |
Points |
PaO2 to FIO2 ratio |
>= 400 |
0 |
|
300 to 399 |
1 |
|
200 to 299 |
2 |
|
100 to 199 and mechanically ventilated |
3 |
|
< 100 and mechanically ventilated |
4 |
platelet count |
>= 150,000 per µL |
0 |
|
100,000 to 149,999 per µL |
1 |
|
50,000 to 99,999 per µL |
2 |
|
20,000 to 49,999 per µL |
3 |
|
< 20,000 per µL |
4 |
Glasgow coma scale |
15 |
0 |
|
13 or 14 |
1 |
|
10 to 12 |
2 |
|
6 to 9 |
3 |
|
3 to 5 |
4 |
serum total bilirubin |
< 1.2 mg/dL |
0 |
|
1.2 to 1.9 mg/dL |
1 |
|
2.0 to 5.9 mg/dL |
2 |
|
6.0 to 11.9 mg/dL |
3 |
|
>= 12 mg/dL |
4 |
mean arterial pressure (with vasopressor) |
>= 70 mm Hg |
0 |
|
< 70 mm Hg |
1 |
pressors (with MAP) |
none |
0 |
|
dopamine <= 5 or any dose dobutamine |
2 |
|
dopamine > 5; epinephrine or norepinephrine <= 0.1 |
3 |
|
epinephrine or norepinephrine > 0.1 |
4 |
serum creatinine |
< 1.2 mg/dL |
0 |
|
1.2 to 1.9 mg/dL |
1 |
|
2.0 to 3.4 mg/dL |
2 |
|
3.5 to 4.9 mg/dL |
3 |
|
>= 5 mg/dL |
4 |
right ventricular score |
LV failure and normal RV function |
0 |
|
LV failure and mild RV failure |
1 |
|
isolated RV failure |
2 |
|
LV failure and moderate RV failure |
3 |
|
LV failure and severe RV failure |
4 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 28
• The higher the score the worse the prognosis.
• A score > 14 had a 30-day overall survival of 44% vs 74% for a score<= 14.
Performance:
• The area under the ROC curve is 0.70.
Specialty: Critical Care, Pulmonology