Components:
(1) study population: items 1 and 2
(2) study validity: items 3, 4, 5
(3) confoounders: items 6, 7, 8
Items:
(1) study groups derived from similar populations
(2) study groups show comparable attrition
(3) exposure measure valid
(4) outcome measure valid
(5) investigators blinded to the endpoint assessment
(6) potential confounders identified
(7) potential confounders are statistically adjusted
(8) no obvious conflicts of interest with funding sources disclosed
Each item is answered Yes or No, with Yes responses considered appropriate.
