Esthesioneuroblastoma is a rare tumor that probably arises from the olfactory neuroepithelium. Kadish et al proposed a staging system for esthesioneuroblastoma. This was modified by Morita et al.
Parameters:
(1) primary site
(2) extension
Primary Site
Extension
Stage
nasal cavity or cranial nerve
none
A
paranasal sinus (maxillary, ethmoid, frontal, sphenoid, accessory)
B
superior nasopharynx
into paranasal sinus
nasal cavity
into sinuses or immediately adjacent structures
as above
direct invasion beyond sinuses; orbital and/or intracranial invasion
C
metastases to cervical lymph node or distant organ
D
where:
• The original Kadish classification used Stages A, B and C, with no distinct group (D) for nodal or distant metastases.
The patient's prognosis is worse with the higher stages.
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Specialty: Hematology Oncology, Surgery, general, Otolaryngology
