Criteria for the diagnosis of VOD:
(1) onset within 20 days after transplantation
(2) 2 or 3 of the following clinical findings:
(2a) hyperbilirubinemia (serum bilirubin > 2 mg/dL)
(2b) hepatomegaly with right upper quadrant pain
(2c) weight gain > 2% from baseline body weight due to fluid accumulation
where:
• Day 0 = day of the marrow infusion.
Uncertain for the diagnosis of VOD:
(1) only 1 of the clinical findings present, OR
(2) other confounding factors present (septicemia, congestive heart failure, pancreatitis, hyperacute graft vs host disease, fungal liver disease, other)
