Worsley et al modified the original Bournemouth score to predict survival in patients with chronic myelomonocytic leukemia. The authors are from Royal Victoria Hospital in Bournemouth.
|
Parameter |
Finding |
Points |
|
hemoglobin |
> 10 g/dL |
0 |
|
|
<= 10 g/dL |
1 |
|
platelet count |
> 100,000 /µL |
0 |
|
|
<= 100,000 /µL |
1 |
|
bone marrow blasts |
< 5% |
0 |
|
|
>= 5% |
1 |
|
neutrophil count |
> 16,000 /µL |
1 |
|
|
2,500 to 16,000 per µL |
0 |
|
|
< 2,500 /µL |
1 |
where:
• For the original Bournemouth score, a neutrophil score = 2,500 would be scored 1 point (<= 2,500).
total score =
= (points for hemoglobin) + (points for platelet count) + (points for bone marrow blasts) + (points for neutrophil count)
Interpretation:
• minimum score: 0
• maximum score: 4
• The lower the score the better the survival.
|
Score |
Group |
Median Survival |
|
0-1 |
A |
32 months |
|
2-4 |
B |
8-9 months |
An additional risk factor was absolute monocyte count > 2,600 per µL. However, analysis of this factor did not reach the same significance as including the increase in the absolute neutrophil count.
Specialty: Hematology Oncology, Clinical Laboratory
ICD-10: ,
