Description

Zhang et al reported models for predicting survival for a patient undergoing surgical resection of a gastric cancer. This can help to identify a patient who may benefit from a more aggressive management. The authors are from Nantong University and affiliated hospitals in China.


Patient selection: gastric cancer undergoing gastrectomy, all age groups

 

Parameters:

(1) location of the cancer

(2) TNM stage

(3) T status

(4) operation

(5) chemotherapy

(6) FPR-PNI (Fibrinogen to Prealbumin Ratio and Prognostic Nutritional Index) score

 

 

Parameter

Finding

Points

location

upper

0

 

middle

22.5

 

lower

54.3

 

total

64.6

TNM stage

I or II

0

 

III or IV

100

T status

T1 or T2

0

 

T3 or T4

42.5

operation

distal gastrectomy

0

 

proximal gastrectomy

36.7

 

total gastrectomy

58

 

palliative

91.7

chemotherapy

no

0

 

yes

27.5

FPR-PNI

0

0

 

1

27.5

 

2

59.1

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

minimum score: 0

maximum score: 385.4

The higher the score the worse the overall survival.

 

value of X =

= (-0.00004308 * ((score)^2)) - (0.007577 * (score)) + 2.596

 

probability of 5-year overall survival =

= 1 / (1 + EXP((-1) * X))

 

Performance:

The area under the ROC curve is 0.74.


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