Patient selection: rectal carcinoma
Outcome: metachronous peritoneal carcinomatosis
Parameters:
(1) age in years
(2) pathologic T stage (pT)
(3) pathologic N stage (pN)
(4) number of examined lymph nodes
(5) completeness of colon resection (R0, R1, R2)
(6) preoperative radiotherapy
(7) adjuvant chemotherapy
|
Parameter
|
Finding
|
Points
|
|
age
|
|
(-0.03 * ((age) - 70)
|
|
pT
|
pT0 to pT2
|
0
|
|
|
pT3
|
1.22
|
|
|
pT4
|
1.86
|
|
pN
|
pN0
|
0
|
|
|
pN1
|
0.88
|
|
|
pN2
|
1.46
|
|
number of lymph nodes
|
0 to 11
|
0.61
|
|
|
>= 12
|
0
|
|
completeness of resection
|
R0
|
0
|
|
|
R1
|
1.35
|
|
|
R2
|
1.42
|
|
preoperative radioatherapy
|
no
|
0
|
|
|
yes
|
-1.03
|
|
adjuvant chemotherapy
|
no
|
0
|
|
|
yes
|
-0.19
|
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: around -2 (depends on age)
• maximum score: around 6.5 (depends on age)
• The higher the score the greater the risk of peritoneal carcinomatosis.
|
Score
|
3-Year Probability of Metachronous Pertinoneal Carcinomatosis
|
|
0
|
4.3
|
|
0.5
|
6.8
|
|
1.0
|
11.1
|
|
1.5
|
17.6
|
|
2.0
|
27.1
|
|
2.5
|
40.3
|
|
3.0
|
54.4
|
|
5.0
|
79.4
|
The data from 0 to 3is approximated by the equation
probability =
= (5.1667 * ((score)^2)) + (1.1643 * (score)) + 4.5476
