Jacobs et al reported models for predicting the outcome following traumatic brain injury (TBI). These can help to identify a patient who may require more aggressive management. The authors are from Radboud University Nijmegen in The Netherlands.
Patient selection: traumatic brain injury, age > 16 years, rated moderate or severe (GCS < 13 after resuscitation)
Outcome: unfavorable by Glasgow Outcome Scale Extended at 6 months (death = GOSE 1; other GOSE 2 to 4)
Parameters:
(1) cisterns
(2) age in years
(3) number of abnormal pupils (0, 1 or 2)
(4) number of contusions
(5) hypotensive episode
(6) abnormal fourth ventricle
(7) dominant lesion (epidural hematoma EDH, subdural hemorrhage SDH, contusion)
Parameter |
Finding |
Points for GOSE 1 |
Points for GOSE 2+ |
cisterns |
compressed |
0.741 |
0.223 |
|
absent |
1.943 |
1.779 |
|
normal |
0 |
0 |
age in years |
|
0.047 * (age) |
0 |
abnormal pupils |
0 |
0 |
0 |
|
1 |
0.321 |
0 |
|
2 |
1.795 |
0 |
number of contusions |
|
0.501 * (number) |
0 |
hypotensive episode |
no |
0 |
0 |
|
yes |
1.067 |
1.198 |
fourth ventricle |
normal |
0 |
0 |
|
abnormal |
1.065 |
0 |
dominant lesion |
EDH |
0 |
0.372 |
|
SDH |
0 |
1.415 |
|
contusion |
0 |
1.320 |
|
none |
0 |
0 |
value of X =
= SUM(points for all of the GOSE 1 parameters) - 4.795
value of Y =
= SUM(points for all of the GOSE 2-4 parameters) - 2.213
probability of death =
= 1 / (1 + EXP((-1) * X))
probability of GOSE 2 to 4 =
= 1 / (1 + EXP((-1) * Y))
Specialty: Surgery, orthopedic