medical decision support medical decision support
Sign In

Model of Yu et al for Preoperative Prediction of Follicular Carcinoma in a Thyroid Nodule

Description

Yu et al reported a model for preoperative prediction of a follicular carcinoma presenting as a thyroid nodule. This can help in surgical planning for the procedure. The authors are from the First Affiliated Hospital of Harbin Medical University in China.


Patient selection: thyroid nodule

 

Parameters:

(1) preoperative serum thyroglobulin concentration in ng/mL

(2) diameter of the nodule in cm

(3) calcifications

(4) nodule composition (totally solid vs any cystic)

(5) blood flow (? by ultrasonography)

 

Parameter

Finding

Points

serum thyroglobulin

 

0.01 * (thyroglobulin)

diameter

 

0.556 * (diameter)

calcifications

no

0

 

yes

0.675

nodule composition

solid

2.355

 

any cystic

0

blood flow

visible (blood flow)

1.072

 

invisible (no blood flow)

0

 

value of X =

= SUM(points for all of the parameters) - 9.787

 

probability of follicular carcinoma =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve is 0.94


To read more or access our algorithms and calculators, please log in or register.

Specialty