Patient selection: status post nephrectomy for renal cell carcinoma. Patients were excluded if there was clinical evidence of distant metastases, metastases to regional lymph nodes, extensive local disease, or extension in the inferior vena cava above the diaphragm.
Parameters:
(1) symptoms at presentation
(2) maximum diameter of the tumor in centimeters
|
Symptoms at Presentation
|
Points
|
|
asymptomatic
|
0
|
|
symptomatic
|
1
|
where:
• A patient was symptomatic if pain, abdominal mass, hematuria and/or weight loss were present.
recurrence risk score =
= (1.55 * (points for presentation)) + (0.19 * (diameter of the tumor in cm))
Interpretation:
• minimum score: around 0.1 (depends on smallest detectable tumor)
• maximum score: around 3.5 (depends on maximum diameter for a nonmetastatic tumor)
|
Recurrence Risk Score
|
Risk of Recurrence
|
Disease Free Survival at 5 Years
|
|
<= 3.00
|
low
|
92%
|
|
> 3.00
|
high
|
57%
|
If the patient is symptomatic, a person becomes high risk when the diameter is > 7.6 cm.
If the patient is asymptomatic, a person becomes high risk when the diameter is > 15.8 cm.
