Description

Some patients with necrotizing fasciitis may present with relatively mild clinical findings, and these patients may not undergo debridement until the disease has progressed to a severe stage of involvement. Wall et al developed a simple model for separating patients with necrotizing fasciitis from those with nonnecrotizing soft tissue infections. The authors are from the Harbor-UCLA Medical Center in Torrance, California.


 

Data:

(1) admission white blood cell (WBC) count

(2) serum sodium, corrected if the glucose was elevated.

 

If the serum glucose is > 200 mg/dL:

 

corrected sodium level in mmol/L =

= (measured sodium in mmol/L) + (0.016 * ((measured glucose in mg/dL) – 100))

 

The model was considered positive if EITHER:

(1) admission WBC > 15,400 per µL

(2) corrected serum sodium was < 135 mEq/L

 

Performance:

• 90% of necrotizing fasciitis and 24% of nonnecrotizing fasciitis patients were considered positive, give a sensitivity of 90% and a specificity of 76%.

• The positive predictive value was 26% and the negative predictive value was 99%

• 61% of patients with necrotizing fasciitis did not have definite clinical signs of necrotizing fasciitis when admitted. 95% of these patients were considered positive by the model.

 


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