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Model of Tutor-Ureta et al for Predicting Outcome in a Patient with Pulmonary Sarcoidosis Based on Bronchoalveolar Lavage (BAL) Neutrophils and NK Cells

Description

Tutor-Ureta et al identified findings on flow cytometry of a bronchoalveolar lavage (BAL) associated with outcome for a patient with pulmonary sarcoidosis. This can help identify a patient who may require more aggressive management. The authors are from Hospital Universitario Puerta de Hierro and Universidad Autonoma de Madrid in Spain.


 

Analysis: flow cytometry of BAL from a patient with pulmonary sarcoidosis

 

Parameters:

(1) percent neutrophils

(2) percent NK cells (lymphocytes positive for CD56)

Percent Neutrophils

Outcome

0%

favorable

1 - 10%

indeterminate

>= 11%

unfavorable

 

Percent NK Cells

Outcome

< 3%

favorable

3 - 5%

indeterminate

> 5%

probably unfavorable

 

where:

• These cutoffs are based on Figure 2 page 420.

 


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