Strand et al reported a model for predicting short-term mortality for a patient undergoing resection of a lung cancer. This can help to identify a patient who may benefit from an alternative therapy. The authors are from the Cancer Registry of Norway.
Patient selection: resection of a lung cancer, age < 90 years
Outcome: 30-day mortality
Parameters:
(1) sex of the patient
(2) age in years
(3) side of the resection
(4) surgical approach
(5) surgical procedure
(6) histopathologic type
(7) pathological stage
(8) hospital volume for the number of lung tumor resections per year
(9) tumor size in cm
Parameter |
Finding |
Beta-Coefficient |
sex |
female |
0 |
|
male |
0.56 |
age in years |
< 50 years |
0 |
|
50 to 59 years |
0.038 |
|
60 to 69 years |
0.47 |
|
70 to 79 years |
1.22 |
|
80 to 89 years |
2.3 |
side |
left |
0 |
|
right |
0.55 |
surgical approach |
VATS |
0 |
|
open thoracotomy |
0.63 |
surgical procedure |
upper lobectomy |
0 |
|
middle lobectomy |
-0.5 |
|
lower lobectomy |
0.42 |
|
bilobectomy |
1.12 |
|
pneumonectomy |
1.51 |
|
sublobar resection |
-0.086 |
histopathologic type |
adenocarcinoma |
0 |
|
squamous cell |
0.078 |
|
other |
0.32 |
pathologic stage |
I |
0 |
|
II |
0.14 |
|
III |
0.21 |
|
IV |
0.98 |
hospital volume |
< 20 cases per year |
0 |
|
>= 20 cases per year |
-0.28 |
tumor size |
<= 3 cm |
0 |
|
3.01 to 5 cm |
-0.073 |
|
> 5 cm |
0.095 |
|
unknown |
0.14 |
value of X =
= SUM(all of the beta-coefficients) - 5.97
probability of 30-day mortality =
= 1 / (1 + EXP((-1) * X))
Specialty: Hematology Oncology