Description

Sasaki et al developed a model for predicting survival after resection of liver metastases from a colorectal adenocarcinoma. This can help to identify a patient who may benefit from more aggressive management. The authors are from Oita University in Japan.


 

Patient selection: colorectal adenocarcinoma with liver metastases

 

Outcome: 5-year survival after surgery

 

Preoperative parameters:

(1) interval between colorectal and hepatic surgery in months

(2) number of liver metastases

(3) preoperative CEA concentration in ng/mL (method not given; ULN reference range apparently < 10 ng/mL)

 

Parameter

Finding

Points

interval between surgeries

< 12 months

1

 

>= 12 months

0

number of liver metastases

1 to 3

0

 

>= 4

1

serum CEA concentration

< 10 ng/mL

0

 

>= 10 ng/mL (elevated)

1

 

total score =

= SUM(points for all 3 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 3

• The higher the score the worse the prognosis.

• 5-year survival without resection was 0% (same as for score of 3).

 

Total Score

5-Year Survival

0

75%

1

54%

2

23%

3

0%

 


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