Description

Parasa et al reported a model for predicting the risk of progression of Barrett's esophagus to neoplasia. This can help to identify a patient who may require more aggressive management. The authors are from multiple institutions in Europe and the United States.


Patient selection: Barrett's esophagus

 

Parameters:

(1) sex

(2) cigarette smoking

(3) length of Barrett's segment in cm

(4) histologically confirmed low-grade dysplasia

 

Parameter

Finding

Points

sex

female

0

 

male

9

cigarette smoking

no

0

 

yes

5

length of segment

 

(length in cm)

confirmed low grade dysplasia

no

0

 

yes

11

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: depends on length of segment, around 32

• The higher the score the greater the risk of progression.

 

Total Score

Risk of Progression

Annual Risk of Progression

0 to 10

low

0.13%

11 to 20

intermediate

0.73%

> 20

high

2.1%

 

Performance:

• The area under the ROC curve is 0.7.


To read more or access our algorithms and calculators, please log in or register.