|To predict the risk of severe complications in a child with sickle cell disease using 3 clinical parameters.|
|Hematology, Internal Medicine/Pediatrics, Hematology, Internal Medicine/Pediatrics, Pediatrics|
|risk factors, laboratory tests, complications|
The risk for a child with sickle cell disease developing severe complications can be predicted based on 3 clinical parameters occurring by the age of 2 years. This can help identify children who may benefit from more intensive therapy and monitoring. The investigators were associated with the Cooperative Study of Sickle Cell Disease and represented several American medical centers.