Description

Medeiros et al developed a model for predicting the risk of progression from ocular hypertension to glaucoma using the data from the Ocular Hypertension Treatment Study (OHTS). The authors are from the Hamilton Glaucoma Center ad the University of California in San Diego.


Parameters:

(1) age

(2) diabetes mellitus

(3) intraocular pressure in mm Hg

(4) central corneal thickness (CCT) in microns (micrometers, µm)

(5) vertical cup to disc ratio

(6) pattern standard deviation (PSD)

 

Parameter

Finding

Points

age in years

40 to 44

0

 

45 to 49

1

 

50 to 54

2

 

55 to 59

3

 

60 to 64

4

 

65 to 69

5

 

70 to 74

6

 

75 to 80

7

diabetes mellitus

no

0

 

yes

-9

intraocular pressure

23 mm Hg

0

 

24

1

 

25

2

 

26

3

 

27

4

 

28

5

 

29

6

 

30 to 31

7

 

32

8

central corneal thickness

670 to 689 microns

0

 

650 to 669

3

 

630 to 649

5

 

610 to 629

8

 

590 to 609

11

 

570 to 589

13

 

550 to 569

16

 

530 to 549

19

 

510 to 529

21

 

490 to 509

24

 

470 to 489

27

 

450 to 459

30

vertical cup to disc ratio

0.1

0

 

0.2

2

 

0.3

5

 

0.4

7

 

0.5

10

 

0.6

12

 

0.7

15

 

0.8

17

 

0.9

20

pattern standard deviation

1.00 to 1.19

0

 

1.20 to 1.39

2

 

1.40 to 1.59

4

 

1.60 to 1.79

6

 

1.80 to 1.99

8

 

2.00 to 2.19

10

 

2.20 to 2.39

12

 

2.40 to 2.59

14

 

where:

• The table is based on the full equations with logarithms as given on page 1353.

• The negative points for diabetes reflects the reduced risk for glaucoma progression.

 

total score =

= SUM(points for all 6 parameters)

 

Interpretation:

• minimum score: -9

• maximum score: 79

• The higher the score the greater the risk for progression to glaucoma within 5 years.

 

Total Score

Percent of Patients Showing Glaucoma at 5 Years

-9 to 12

< 1%

13 - 27

1 - 5%

28 - 33

6 - 10%

34 - 37

11 - 15%

38 - 40

16 - 20%

41 - 44

21 - 30%

45 - 47

31 - 40%

48 - 50

41 - 50%

51 - 79

> 50%

 


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