Loots et al reported a model for the early diagnosis of sepsis in an adult in primary care. The authors are from multiple institutions in the Netherlands.
Patient selection: adult in primary care
Parameters:
(1) age of the patient in years
(2) tympanic temperature in °C
(3) systolic blood pressure in mm Hg
(4) heart rate in beats per minute
(5) peripheral oxygen saturation in percent
(6) mental status
Parameter
Finding
Points
age
<= 65 years
0
> 65 years
1
temperature
<= 38°C
0
> 38°C
1
systolic blood pressure
<= 110 mm Hg
1
> 110 mm Hg
0
heart rate
<= 110 beats per minute
0
> 110 beats per minute
1
oxygen saturation
> 95%
0
<= 95%
1
mental status
normal
0
altered
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
• The diagnosis assumes that other explanations for the findings (like drug overdose) have been ruled out.
Total Score
Percent Sepsis
0
< 1%
1
5%
2
15%
3
37%
4
70%
5
88%
6
97%
Performance:
• The area under the ROC curve was 0.80.
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