Liu et al reported a nomogram to help distinguish Kawasaki disease from sepsis in a young child. The authors are from Shenzhen Baoan Women's and Children's Hospital and Jinan University in China and Kaohsiung Chang Gung Memorial Hospital in Taiwan.
Patient selection: fever in a child less than 5 years old
Parameters:
(1) WBC count in 10^9/L
(2) hemoglobin level
(3) procalcitonin in ng/mL
(4) serum CRP in mg/L
(5) serum albumin in g/L
(6) serum ALT in U/L
Parameter
Finding
Points
WBC count
>= 19.71 * 10^9/L
0
< 19.71 * 10^9/L
96.1
hemoglobin level
normal
0
low (anemia)
40.4
procalcitonin
> 0.5 ng/mL
0
<= 0.5 ng/mL
57.7
serum CRP
>= 59.11
0
< 59.11
52.7
serum albumin
>= 39.35 g/L
0
< 39.35 g/L
58.6
serum ALT
<= 40 IU/L
0
> 40 U/L
100
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 405.5
• A score > 175 is associated with a high risk of Kawasaki disease.
value of X =
= (0.02142 * (score)) - 3.756
probability of Kawasaki disease =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.87.
To read more or access our algorithms and calculators, please log in or register.
