Description

Lin et al reported a simple score for early prediction of sepsis in an older adult. The authors are from Taipei Medical University.


Patient selection: age >= 60 years

 

Parameters:

(1) modified early warning score (MEWS)

(2) white blood cell count in 10^9/L

(3) neutrophil-to-lymphocyte ratio (NLR)

(4) monocyte distribution width (MDW), presumably in IU

 

Parameter

Finding

Points

MEWS

< 3

0

 

>= 3

1

WBC count

< 11 * 10^9/L

0

 

>= 11 * 10^9/L

1

NLR

< 8

0

 

>= 8

1

MDW

< 20

0

 

>= 20

2

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 5

• A score >= 3 had the highest Youden index.

 

Performance:

• The area under the ROC curve varied from 0.89 to 0.82 depending on age group.


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