Kling et al identified factors associated with blood transfusion in premature infants in the intensive care unit (ICU). This can help identify infants who may benefit from erythropoietin therapy. The authors are from the Arizona Health Sciences Center.


Infant selection: birthweight was <= 1,500 grams



(1) SNAP score on day 7 (Score for Neonatal Acute Physiology)

(2) blood loss from phlebotomy in mg per kg per day (where the average blood loss per day will be used in the implementation)


NOTE: I am not sure how this data could be used before day 7 in the ICU. Its main use must be for likelihood of transfusion during long ICU admissions.


X =

= (0.538 * (SNAP on day 7)) + (4.136 * (blood loss in mg per kg per day)) - 11.459


probability of blood transfusion =

= 1 / (1 + EXP((-1) * X))


The average blood transfusion was 12 mL per kg.


All infants who received transfusions from day 0 to 7 received blood transfusions after day 7.


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