Iliuta et al used kinetic models to determine the duration of hemodialysis sessions for the treatment of acute ethylene glycol poisoning. The authors are from Universite Laval, University of Montreal and CHU de Quebec Research Center in Canada.
Molecular weight of ethylene glycol: 62.07
1 mmol/L = 6.2 mg/dL
Dialysis settings:
(1) blood flow > 300 mL per minute
(2) dialysate flow 500-800 mL per minute
(3) membrane surface area > 2 square meters
Target serum level: 2 mmol/L or less
Metabolic acidosis must be corrected for estimates to be valid.
Parameters:
(1) initial ethylene glycol concentration in mmol/L