Model of Herder et al for Probability of Lung Cancer in a Solitary Lung Nodule Based on Swensen Score and Findings of FDG-PET Scan

Description

Herder et al developed a model for predicting whether a solitary lung nodule is malignant or not. This is based on both the probability from the Swensen equation and findings on 18F-fluorodeoxyglucose positron emission tomography. The authors are from VU University Medical Centre and the Comprehensive Cancer Centre in Amsterdam.

Patient selection: solitary lung nodule

Parameters:

(1) probability of lung cancer from equation of Swensen et al

(2) findings on 18F-FDG-PET

points from Swensen score =

= (0.77 * (probability lung cancer))

FDG-PET Scan	Points
normal	0
faint	48.6
moderate	96.6
intense	100

total score =

= (points from Swensen) + (points for PET scan)

Score	Probability Lung Cancer
0 to 53	< 10%
53 to 99	(0.009483 * ((points)^2)) - (0.5665 * (points)) + 13.27
99 to 145	(-0.008907 * ((points)^2)) + (3.048 * (points)) - 164.6
> 145	> 90%

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Description

Specialty

ICD-10