Description

Grant et al developed a model for predicting in-hospital mortality following an elective repair of an abdominal aortic aneurysm. This can help guide patient management, especially in high risk patients. The authors are from the University of Manchester, University Hospital of South Manchester, Northwest Institute for Bio-Health Informatics, Liverpool Heart and Chest Hospital and the Vascular Audit Committee of the Royal College of Surgeons.


Patient selection: elective abdominal aortic aneurysm

 

Outcome: in-hospital mortality

 

Parameters:

(1) type of surgical repair

(2) age in years

(3) gender

(4) serum creatinine in µmol/L

(5) cardiac disease

(6) ECG

(7) white blood cell count

(8) serum sodium concentration

(9) diameter of the aortic aneurysm in cm

(10) ASA fitness grade

(11) previous aortic surgery or stent

 

Parameter

Finding

Points

type of surgical repair

open

1.6466

 

other

0

age in years

 

(0.0568 * (age))

gender

male

0

 

female

0.7062

serum creatinine

<= 120 µmol/L

0

 

> 120 µmol/L

0.5979

cardiac disease

no

0

 

yes

0.3422

ECG

normal

0

 

abnormal

0.3033

WBC

normal

0

 

abnormal (< 3 or > 11 *10^9/L)

0.3697

serum sodium

normal

0

 

abnormal (< 135 or > 145 mmol/L)

0.3099

diameter of aneurysm

 

(0.1285 * (diameter))

ASA grade

I

0

 

II

0.2292

 

III

0.7334

 

IV

1.6775

previous aortic surgery or stent

no

0

 

yes

0.8812

 

X =

= SUM(points for all 11 parameters) - 10.9187

 

probability of in-hospital mortality =

= 1 / (1 + EXP((-1) * X))

 

Probability

Risk Group

Observed Mortality

<= 1.5%

low

0.8%

1.51 to 3.3%

medium

2.3%

> 3.3%

high

7%

 

Performance:

• The area under the ROC curve was 0.78.


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