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Description

Freundlich et al reported a predictive model for reintubation of cardiac surgery patient within 48 hours. The authors are from Vanderbilt University.


Patient selection: cardiac surgery

 

Outcome: reintubation within 48 hours of post-operative extubation

 

Parameters:

(1) number of inotropes

(2) time to extubation in hours

(3) dexmedotomidine dose in µg/kg per hour

(4) increased in breaths per minute

 

Parameter

Findings

Points

number of inotropes

0

0

 

1

2.734

 

>= 2

4.139

time to extubation

 

0.036 * (hours) / 6

dexmedotomidine

 

1.111 * (dose)

respiratory rate

 

0.041 * (breaths per min)

 

value of X =

= SUM(points for all of the parameters) - 6.949

 

probability of reintubation =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve is 0.86.


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