Description

Chin et al reported a model for predicting post-hepatectomy liver failure (PHLF). This can help to identify a patient who may require more aggressive management or an alternative treatment. The authors are from Singapore General Hospital and Duke-National University of Singapore.


Patient selection: hepatectomy for hepatocellular carcinoma

 

Parameters:

(1) ALBI score of Johnson et al

(2) serum total bilirubin on postoperative day 1 in mg/dL

(3) serum total bilirubin prior to surgery in mg/dL

(4) pre-operative prothrombin time in seconds

 

Parameter

Points

ALBI score

0.66698 * (ALBI)

pre and post-op bilirubins

1.69134 * LN(postop/Preop)

prothrombin time

0.69737 * (PT)

 

value of X =

= SUM(points for the parameters) - 10.47046

 

probability of PHLF =

= 1 / (1 + EXP((-1) * X))

 

Performance:

• The area under the ROC curve is 0.88.


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