Chin et al reported a model for predicting post-hepatectomy liver failure (PHLF). This can help to identify a patient who may require more aggressive management or an alternative treatment. The authors are from Singapore General Hospital and Duke-National University of Singapore.
Patient selection: hepatectomy for hepatocellular carcinoma
Parameters:
(1) ALBI score of Johnson et al
(2) serum total bilirubin on postoperative day 1 in mg/dL
(3) serum total bilirubin prior to surgery in mg/dL
(4) pre-operative prothrombin time in seconds
Parameter
Points
ALBI score
0.66698 * (ALBI)
pre and post-op bilirubins
1.69134 * LN(postop/Preop)
prothrombin time
0.69737 * (PT)
value of X =
= SUM(points for the parameters) - 10.47046
probability of PHLF =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.88.
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