Chen et al reported a model for predicting malignancy in a small
The authors are from Zhejiang University, Jinhua Central Hospital and Taizhou First People's Hospital in China.
Patient selection: pulmonary nodule <= 10 mm in diameter on high-resolution chest CT
Parameters:
(1) lung nodule density in HU
(2) vascular penetration sign (pulmonary artery passes through the nodule)
(3) nodule type (solid, ground glass, mixed)
(4) incisure surrounding the nodule (notch in the outer wall)
|
Parameter
|
Finding
|
Points
|
|
density in HU
|
|
- 0.004 * (density)
|
|
vascular penetration sign
|
present
|
1.096
|
|
|
absent
|
0
|
|
nodule type
|
mixed ground glass
|
1.198
|
|
|
solid or pure ground glass
|
0
|
|
incisure
|
absent
|
0
|
|
|
present
|
-1.811
|
score =
= SUM(points for all of the parameters) - 2.957
probability
= 1 / (1 + EXP((-1) * (score)))
Performance:
• The area under the ROC curve is 0.74.
