Cecatto et al identified risk factors for pharyngocutaneous fistula following total laryngectomy for cancer. This can help identify a patient who may require more aggressive management. The authors are from multiple insitutions in Brazil and Portugal.
Patient selection: total laryngectomy for cancer
Parameters:
(1) ASA classification (either 2 or 3)
(2) alcohol consumption
(3) chemoradiotherapy prior to surgery
(4) tracheotomy prior to surgery
(5) hemoglobin prior to surgery in 6/dL
(6) local extension
(7) N-classification (from 0 to 3)
(8) diabetes mellitus
(10) serum albumin prior to surgery in g/L
Parameter |
Finding |
Point |
ASA classification |
|
4.98 * (ASA) |
alcohol consumption |
heavy |
1.97 |
|
not heavy |
0 |
chemoradiotherapy |
no |
0 |
|
yes |
5.10 |
tracheotomy |
no |
0 |
|
yes |
2.40 |
hemoglobin |
>= 12.4 g/dL |
0 |
|
< 12.4 |
0.75 |
local extension |
no |
0 |
|
yes |
0.69 |
N classification |
|
1.01 * (N class) |
diabetes mellitus |
no |
0 |
|
yes |
0.75 |
albumin |
>= 37 g/L |
0 |
|
<= 37 g/L |
3.03 |
where:
• The handling of hemoglobin, N classification, and albumin is ambiguous.
total score =
= SUM(points for all of the parameters)
Interpretation:
• The higher the score the greater the risk of a fistula.
Score |
Risk |
Fistula |
<= 9.88 (?? 9.96) |
low |
11% |
low to medium |
20% |
|
12.26 to 17.1 |
medium to high |
27% |
> 17.1 |
high |
76% |
Performance:
• The area under the ROC curve is 0.76.
Specialty: Hematology Oncology, Endocrinology