Description

Cecatto et al identified risk factors for pharyngocutaneous fistula following total laryngectomy for cancer. This can help identify a patient who may require more aggressive management. The authors are from multiple insitutions in Brazil and Portugal.


Patient selection: total laryngectomy for cancer

 

Parameters:

(1) ASA classification (either 2 or 3)

(2) alcohol consumption

(3) chemoradiotherapy prior to surgery

(4) tracheotomy prior to surgery

(5) hemoglobin prior to surgery in 6/dL

(6) local extension

(7) N-classification (from 0 to 3)

(8) diabetes mellitus

(10) serum albumin prior to surgery in g/L

 

Parameter

Finding

Point

ASA classification

 

4.98 * (ASA)

alcohol consumption

heavy

1.97

 

not heavy

0

chemoradiotherapy

no

0

 

yes

5.10

tracheotomy

no

0

 

yes

2.40

hemoglobin

>= 12.4 g/dL

0

 

< 12.4

0.75

local extension

no

0

 

yes

0.69

N classification

 

1.01 * (N class)

diabetes mellitus

no

0

 

yes

0.75

albumin

>= 37 g/L

0

 

<= 37 g/L

3.03

 

where:

The handling of hemoglobin, N classification, and albumin is ambiguous.

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

The higher the score the greater the risk of a fistula.

 

Score

Risk

Fistula

<= 9.88 (?? 9.96)

low

11%

9.881 (??9.97) to 12.25

low to medium

20%

12.26 to 17.1

medium to high

27%

> 17.1

high

76%

 

Performance:

The area under the ROC curve is 0.76.


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