Description

Castellanos-Ortega et al developed a scoring system for predicting the prognosis for a child with meningococcal septic shock. This can help identify a child who may benefit from more aggressive management or novel therapies. The authors are from multiple university hospitals in Spain.


 

Parameters:

(1) refractory hypotension

(2) base deficit (opposite of base excess)

(3) Glasgow Coma Scale

(4) leukocyte count

(5) aPTT

(6) cyanosis

(7) oliguria

 

Parameter

Finding

Points

refractory hypotensions

absent

0

 

present

2

base deficit

<= 10 mmol/L

0

 

> 10 mmol/L (severe acidosis)

1

Glasgow Coma score

8 to 15

0

 

3 to 7

2

leukocyte count

>= 4,000 per µL

0

 

< 4,000 per µL

1

aPTT

<= 1.5 times control

0

 

> 1.5 times control

1

cyanosis

absent

0

 

present

2

oliguria

absent

0

 

present

1

 

where:

• Several of the parameters are indicators for multiple organ failure.

• I will use the upper limit of reference range for the aPTT in the implementation rather than a control value in the implementation. Alternatively the mean of the reference range could be used, but this would only be a minor elevation in some laboratories.

 

total score =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 10

• The higher the score the worse the prognosis.

 

Total Score

Risk Group

Probability of Death

0 to 3

low

3%

4 or 5

intermediate

26%

6 to 10

high

74%

 


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