Buendia and Feliciano-Alfonso reported a model for identifying inappropriate antibiotic therapy in an infant with acute bronchiolitis. The authors are from Universidad de Antioqua in Medllin, Columbia.
Patient selection: < 2 years of age with acute bronchiolitis
Parameters:
(1) chest retractions
(2) temperature in °C
(3) white blood cell count per µL
(4) age in moths
Parameter
Finding
Points
chest retractions
no
0
yes
1
temperature °C
< 37.5°C
0
37.5 to 38.5°C
1
> 38.5°C
0
WBC
< 10,000 per µL
0
10,000 to 15,000
2
age in months
<= 12 months
0
12.01 to 24 months
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
• A score > 2 indicates an infant who should be re-evaluated for use of antibiotics.
Score
Risk Inappropriate
0
29%
1
53%
2
75%
3
89%
4
96%
5
98%
Performance:
• The area under the ROC curve is 0.67.
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