Bourdel-Marchasson et al reported a model for 1-year mortality for an older adult with cancer. The authors are from CHU Bordeaux, Bordeaux University, INSERM Bordeaux and InstitutBergonie in France.
Patient selection: cancer patient > 70 years of age
Parameters:
(1) food intake over the past 3 months
(2) number of prescription drugs taken per day
(3) protein-rich food intake
(4) calf circumference in centimeters
(5) cancer origin
(6) metastases
(7) absolute lymphocyte count per microliter
Parameter |
Finding |
Points |
food intake |
severe decrease |
13.4 |
|
moderate decrease |
7.1 |
|
no decrease |
0 |
prescription drugs |
0 to 3 |
0 |
|
>= 4 |
4.8 |
protein rich food intake |
low |
10 |
|
intermediate |
5.2 |
|
high |
0 |
calf circumference |
< 31 cm |
11.3 |
|
>= 31 cm |
0 |
cancer origin |
non-small cell lung |
18.6 |
|
colon |
0 |
|
stomach |
10.4 |
|
ovary |
0.8 |
|
pancreas |
15.1 |
|
cholangiocarcinoma |
10.7 |
|
unknown |
7 |
|
prostate |
6.4 |
|
breast |
6 |
|
bladder |
13.8 |
metastases |
no |
0 |
|
yes |
8.8 |
lymphocyte count |
< 1,500 per µL |
8.4 |
|
>= 1,500 per µL |
0 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 75.2
Total Score |
1-Year Mortality |
<= 21 |
19.5% |
22 to 30 |
|
>= 31 |
70% |
Performance:
• The area under the ROC curve is 0.79 in the derivation and 0.70 in the validation cohorts.
Specialty: Hematology Oncology