Description

Ariyaratne et al developed a model for predicting early mortality following aortic valve replacement. This can help to identify a patient who may benefit from more aggressive management. The authors are from The Alfred Centre in Melbourne, the Geelong Hospital and Monash University in Australia.


 

Patient selection: aortic valve replacement surgery

 

Outcome: early death

 

Parameters:

(1) cerebrovascular disease

(2) grade of left ventricular ejection fraction LVEF)

(3) NYHA class

(4) previous cardiac surgery

(5) active infective endocarditis

(6) left main coronary artery disease

(7) renal dysfunction based on estimated GFR

(8) age in years

 

Parameter

Finding

Points

Beta

cerebrovascular disease

none

0

0

 

coma

3

0.805

 

CVA

2

0.422

 

RIND/TIA

2

0.417

LVEF

normal

0

0

 

mild

1

0.233

 

moderate

1

0.377

 

severe

3

0.742

NYHA class

I or II

0

0

 

III

2

0.557

 

IV

4

1.129

previous cardiac surgery

none

0

0

 

previous CABG

4

0.959

 

previous valve surgery

1

0.256

 

previous other cardiac surgery

6

1.425

active infective endocarditis

no

0

0

 

yes

5

1.351

left main coronary artery disease

no

0

0

 

yes

3

0.775

renal dysfunction

none

0

0

 

mild

3

0.789

 

moderate

4

0.990

 

severe

7

1.873

 

end-stage

7

1.909

age

< 60 years

0

0

 

60 to 69 years

2

0.576

 

70 to 79 years

4

1.122

 

>= 80 years

6

1.564

 

total score =

= SUM(points for all 8 parameters)

 

value of X =

= SUM(beta coefficients) – 6.084

 

probability of early mortality =

= 1 / (1 + EXP((-1) * X))

 

Interpretation:

• minimum score: 0

• maximum score: 37

• The higher the score the greater the risk of early mortality.

 

Total Score

Probability of Mortality

0 to 12

(0.0655 * ((score)^2)) - (0.506 * (score)) + 1.747

12 to 25

(0.2145 * ((score)^2)) - (3.59 * (score)) + 16.67

> 25

> 60%

 


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