Martin et al reported criteria for classifying HELLP (hemolysis, elevated liver enzymes, low platelets). The authors are from the University of Mississipi in Jackson.

Patient selection: HELLP syndrome



(1) platelet count per microliter

(2) serum transaminases (AST or ALT) in IU/L

(3) serum LDH in IU/L



Severe (Class 3)

Moderate (Class 2)

Mild (Class 1)

Platelet Count

< 50,000 per µL

50,000 to 99,999 per µL

100,000 to 150,000 per µL


>= 70 IU/L

>= 70 IU/L

40 to 69 IU/L


>= 600 IU/L

>= 600 IU/L

>= 600 IU/L



• The platelet count appears to be the main metric used for classifying.


Severe HELLP is associated with slower recovery and a higher rate of requiring plasma exchange.

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