Description

Sivayoham et al reported the MISSED score for evaluating a patient with sepsis in the Emergency Department. This can help to identify a patient who may require more aggressive management. The authors are from St. George's Healthcare NHS Trust in London.


MISSED is an acronym for Mortality In Severe Sepsis in the Emergency Department.

 

Patient selection: severe sepsis in the Emergency Department

Parameters:

(1) age in years

(2) serum albumin in g/L

(3) INR

 

Parameter

Finding

Points

age in years

< 65 years

0

 

>= 65 years

2.5

serum albumin

> 27 g/L

0

 

<= 27 g/L

3

INR

< 1.2

0

 

>= 1.2

3.5

 

total score =

= SUM(points for all 3 parameters)

 

Interpretation:

minimum score: 0

maximum score: 9

The higher the score the greater the mortality.

 

MISSED Score

Mortality Rate in Derivation Cohort

Mortality Rate in Validation Cohort

0

0%

7%

< 5.5

37%

17%

>= 5.5

45%

41%

9

56%

63%

 

Performance:

The area under the ROC curve was 0.71 for the derivation cohort.


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