The minimum intervals between donations for various blood products in the United States are determined by the Food and Drug Administration (FDA). The intervals are dependent on the time it takes for the body to replenish the harvested component.
Bllod Product
Minimum Interval (Days)
Maximum per Year
whole blood
56
red cell apheresis
56
double red cell apheresis
112 (two times single)
3
plasma apheresis
28
platelet apheresis
7
24
Component
Usual Time to Recovery
plasma
48 hours
platelets
72 hours
red blood cells
4-6 weeks
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