Diagnostic Criteria for Adverse Pulmonary Events Resulting from Methotrexate Therapy

Does the patient have hypersensitivity pneumonitis by pathology without evidence of pathogenic organisms?

Is there radiologic evidence of pulmonary interstitial or alveolar infiltrates?

Is the patient febrile?

Are blood cultures positive for pathogenic organisms?

Does the patient have a productive cough?

Are sputum cultures positive for pathogenic organisms?

Does the patient have a nonproductive cough?

Has the person had shortness of breath?

Duration of shortness of breath

Oxygen saturation in percent on room air at initial evaluation (enter from 0 to 100)

Diffusing capacity of the lung for carbon monoxide

Predicted diffusing capacity of the lung for carbon monoxide for age

WBC count