Smit et al reported a method for dosing gentamicin in an obese adult. Th authors are from St. Antonius Hospital, Leiden University, Radboud Institute for Health Sciences and Erasmus MC in The Netherlands.
Patient selection: obese patient with normal renal function (eGFR > 60 mL per minute)
Dosing level of gentamicin: 5 mg/kg
dosing weight for a patient >= 100 kilograms =
= 70 * (((weight) / 70)^0.73)
Weight in Kilograms
Gentamicin Dose in mg
< 100 kg
5 * (weight)
100 to 120 kg
480
120 to 140 kg
560
140 to 160 kg
600
160 to 180 kg
680
180 to 200 kg
760
200 to 220 kg
800
> 220 kg
use alternative method
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