Description

McNamara et al used 4 clinical parameters (1 historical, 1 radiologic, 1 from the ECG, 1 laboratory test) to predict if the left ventricular ejection fraction (LVEF) was > 0.40. This is a simple assessment that can be performed without complex equipment. The authors are from the University of Rochester in New York.


 

Parameters:

(1) location of the acute infarct

(2) chest X-ray findings

(3) history of a previous myocardial infarction

(4) serum creatine kinase

 

Parameter

Odds Ratio for LVEF <= 0.40

anterior MI

4.7

pulmonary congestion on chest X-ray

2.9

history of previous MI

2.3

serum CK > 1,000 units

2.1

from Table II, page 194

 

Parameter

Finding

Points

location of the acute MI

anterior

1

 

other than anterior

0

pulmonary congestion on chest X-ray

present

1

 

absent

0

history of previous MI

present

1

 

absent

0

serum CK

> 1,000 units

1

 

<= 1,000 units

0

 

score =

= SUM(points for all 4 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 4

• The higher the score, the more likely that the LVEF was <= 0.40.

Score

Accuracy

0 or 1

80% for LVEF > 0.40

2, 3 or 4

72% for LVEF <= 0.40

 

Performance:

• Clinically significant major misclassifications were < 10%.

• Problems tended to occur for scores of 2, with these patients having a LVEF close to the breakpoint of 0.40 (page 195)

 

Limitations:

• The methodology and normal range for the serum CK is not given. By any method this would be indicate a sizable infarct.

 


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