Early work by Jelliffe for estimating creatinine clearance from serum creatinine included different equations for men and women, but did not include weight or age as variables.


creatinine clearance for males =

= ((100 / (serum creatinine in mg/dL)) - 12) mL/min per 1.73 meters-squared


creatinine clearance for females =

= ((80 / (serum creatinine in mg/dL)) - 7) mL/min per 1.73 meters-squared


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